pentobarbital will decrease the extent or impact of colchicine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will lower the level or impact of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Strong CYP3A4 inducers are envisioned to trigg